Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates

被引：99

作者：

Herzog, ED ^{[1
]}

Geusz, ME ^{[1
]}

Khalsa, SBS ^{[1
]}

Straume, M ^{[1
]}

Block, GD ^{[1
]}

机构：

[1] UNIV VIRGINIA, DEPT INTERNAL MED, CHARLOTTESVILLE, VA 22903 USA

来源：

BRAIN RESEARCH | 1997年 / 757卷 / 02期

关键词：

suprachiasmatic nucleus; circadian rhythm; pacemaker; planar electrode array;

D O I：

10.1016/S0006-8993(97)00337-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The suprachiasmatic nucleus (SCN) of the mammalian hypothalamus functions as a circadian pacemaker. This study used multimicroelectrode plates to measure extracellular action potential activity simultaneously from multiple sites within the cultured mouse SCN. Neurons within the isolated mouse SCN expressed a circadian rhythm in spontaneous firing rate for weeks in culture.

引用

页码：285 / 290

页数：6

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