Alkaloid accumulation in Catharanthus roseus cell suspension cultures fed with stemmadenine

被引：27

作者：

El-Sayed, M

Choi, YH

Frédérich, M

Roytrakul, S

Verpoorte, R ^{[1
]}

机构：

[1] Leiden Univ, Inst Biol, Metab Sect, Dept Pharmacognosy, Leiden, Netherlands

[2] S Valley Univ, Fac Sci, Dept Bot, Aswan, Egypt

来源：

BIOTECHNOLOGY LETTERS | 2004年 / 26卷 / 10期

关键词：

alkaloid accumulation Catharanthus roseus; cell culture condylocarpine; stemmadenine; tabersonine-catharanthine pathway;

D O I：

10.1023/B:BILE.0000025879.53632.f2

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Feeding stemmadenine to Catharanthus roseus cell suspension culture resulted in the accumulation of catharanthine, tabersonine and condylocarpine. Condylocarpine is not an intermediate in the pathway to catharanthine or tabersonine when it is fed to the cultures. The results support the hypothesis that stemmadenine is an intermediate in the pathway to catharanthine and tabersonine.

引用

页码：793 / 798

页数：6

共 14 条

[1] REARRANGEMENT OF CATHARANTHINE, STEMMADENINE AND TABERSONINE IN ACETIC ACID [J].