Surface-enhanced laser desorption ionization time-of-flight mass spectrometry (SELDI TOF-MS) and ProteinChip® technology in proteomics research

被引：95

作者：

Seibert, V

Wiesner, A

Buschmann, T

Meuer, J

机构：

[1] EUROPROTEOME AG, D-16761 Hennigsdorf, Germany

[2] Ciphergen Biosyst GmbH, D-37085 Gottingen, Germany

来源：

PATHOLOGY RESEARCH AND PRACTICE | 2004年 / 200卷 / 02期

关键词：

SELDI; ProteinChipu((R)) system; oncology; toxicology; immunology;

D O I：

10.1016/j.prp.2004.01.010

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

In this review article, we describe some of the studies that have been performed using the surface-enhanced laser desorption ionization (SELDI) time-of-flight mass spectrometry and ProteinChip((R)) technology over the past few years, and highlight both their findings as well as limitations. Proteomic applications, such as target or marker identification and target validation or toxicology, will be addressed. We will also provide an examination of SELDI technology and go into the question of where possible future research may lead us. (C) 2004 Elsevier GmbH. All rights reserved.

引用

收藏

页码：83 / 94

页数：12

相关论文

共 34 条

[1]

Adam BL, 2002, CANCER RES, V62, P3609

[2] Proteome and proteomics: New technologies, new concepts, and new words [J].

Anderson, NL ;

Anderson, NG .

ELECTROPHORESIS, 1998, 19 (11) :1853-1861

[3] Viral binding proteins as antibody surrogates in immunoassays of cytokines [J].

Bai, HD ;

Buller, RML ;

Chen, NH ;

Boyle, MDP .

BIOTECHNIQUES, 2002, 32 (01) :160-+

[4] Generation of C-terminally truncated amyloid-β peptides is dependent on γ-secretase activity [J].

Beher, D ;

Wrigley, JDJ ;

Owens, AP ;

Shearman, MS .

JOURNAL OF NEUROCHEMISTRY, 2002, 82 (03) :563-575

[5] Cell sampling - Laser capture microdissection: Molecular analysis of tissue [J].

Bonner, RF ;

EmmertBuck, M ;

Cole, K ;

Pohida, T ;

Chuaqui, R ;

Goldstein, S ;

Liotta, LA .

SCIENCE, 1997, 278 (5342) :1481-&

[6] A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease [J].

Carrette, O ;

Demalte, I ;

Scherl, A ;

Yalkinoglu, O ;

Corthals, G ;

Burkhard, P ;

Hochstrasser, DF ;

Sanchez, JC .

PROTEOMICS, 2003, 3 (08) :1486-1494

[7] Surface chemistries enabling photoinduced uncoupling/desorption of covalently tethered biomolecules [J].

Ching, J ;

Voivodov, KI ;

Hutchens, TW .

JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (11) :3582-3583

[8]

Dare TO, 2002, ELECTROPHORESIS, V23, P3241, DOI 10.1002/1522-2683(200209)23:18<3241::AID-ELPS3241>3.0.CO

[9]

2-D

[10] Use of ProteinChip™ array surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) to identify thymosin β-4, a differentially secreted protein from lymphoblastoid cell lines [J].

Diamond, DL ;

Zhang, YN ;

Gaiger, A ;

Smithgall, M ;

Vedvick, TS ;

Carter, D .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2003, 14 (07) :760-765

← 1 2 3 4 →