Low serum IGF-1 and occurrence of osteoporotic fractures in postmenopausal women

被引：129

作者：

Garnero, P ^{[1
]}

Sornay-Rendu, E ^{[1
]}

Delmas, PD ^{[1
]}

机构：

[1] Hop Edouard Herriot, INSERM, U403, F-69437 Lyon 03, France

来源：

LANCET | 2000年 / 355卷 / 9207期

关键词：

D O I：

10.1016/S0140-6736(99)05463-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The link between serum insulin-like growth factor 1 (IGF-1) and postmenopausal osteoporosis remains controversial. In this study of healthy postmenopausal women, decreased serum concentrations of IGF-1 were strongly associated with an increased risk of osteoporotic fractures independently of bone-mineral density.

引用

页码：898 / 899

页数：2

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