The inflammasome - A linebacker of innate defense

[1] De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID) -: A new member of the expanding family of pyrin-associated autoinflammatory diseases [J]. ARTHRITIS AND RHEUMATISM, 2002, 46 (12): : 3340 - 3348

[2] Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (01) : 198 - 203

[3] Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome [J]. NATURE GENETICS, 2001, 29 (03) : 301 - 305

[4] Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3 [J]. NATURE, 2006, 440 (7081) : 233 - 236

[5] Mariathasan S, 2006, NATURE, V440, P228, DOI 10.1038/nature04515

[6] Gout-associated uric acid crystals activate the NALP3 inflammasome [J]. NATURE, 2006, 440 (7081) : 237 - 241

[1] De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID) -: A new member of the expanding family of pyrin-associated autoinflammatory diseases [J]. ARTHRITIS AND RHEUMATISM, 2002, 46 (12): : 3340 - 3348

[2] Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (01) : 198 - 203

[3] Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome [J]. NATURE GENETICS, 2001, 29 (03) : 301 - 305

[4] Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3 [J]. NATURE, 2006, 440 (7081) : 233 - 236

[5] Mariathasan S, 2006, NATURE, V440, P228, DOI 10.1038/nature04515

[6] Gout-associated uric acid crystals activate the NALP3 inflammasome [J]. NATURE, 2006, 440 (7081) : 237 - 241