Computational biology and high-performance computing

被引:15
作者
Bader, DA [1 ]
机构
[1] Univ New Mexico, Dept Elect & Comp Engn, Albuquerque, NM 87131 USA
[2] Univ New Mexico, Dept Comp Sci, Albuquerque, NM 87131 USA
关键词
D O I
10.1145/1029496.1029523
中图分类号
TP3 [计算技术、计算机技术];
学科分类号
0812 ;
摘要
Understanding evolution and the basic structure and function of proteins are two grand challenge problems in biology that can be solved only through the use of high-performance computing.
引用
收藏
页码:34 / 41
页数:8
相关论文
共 13 条
[1]   Blue Gene: A vision for protein science using a petaflop supercomputer [J].
Allen, F ;
Almasi, G ;
Andreoni, W ;
Beece, D ;
Berne, BJ ;
Bright, A ;
Brunheroto, J ;
Cascaval, C ;
Castanos, J ;
Coteus, P ;
Crumley, P ;
Curioni, A ;
Denneau, M ;
Donath, W ;
Eleftheriou, M ;
Fitch, B ;
Fleischer, B ;
Georgiou, CJ ;
Germain, R ;
Giampapa, M ;
Gresh, D ;
Gupta, M ;
Haring, R ;
Ho, H ;
Hochschild, P ;
Hummel, S ;
Jonas, T ;
Lieber, D ;
Martyna, G ;
Maturu, K ;
Moreira, J ;
Newns, D ;
Newton, M ;
Philhower, R ;
Picunko, T ;
Pitera, J ;
Pitman, M ;
Rand, R ;
Royyuru, A ;
Salapura, V ;
Sanomiya, A ;
Shah, R ;
Sham, Y ;
Singh, S ;
Snir, M ;
Suits, F ;
Swetz, R ;
Swope, WC ;
Vishnumurthy, N ;
Ward, TJC .
IBM SYSTEMS JOURNAL, 2001, 40 (02) :310-327
[2]   A linear-time algorithm for computing inversion distance between signed permutations with an experimental study [J].
Bader, DA ;
Moret, BME ;
Yan, M .
JOURNAL OF COMPUTATIONAL BIOLOGY, 2001, 8 (05) :483-491
[3]   PROPOSED MOLTEN GLOBULE INTERMEDIATES IN FD PHAGE PENETRATION AND ASSEMBLY [J].
DUNKER, AK ;
ENSIGN, LD ;
ARNOLD, GE ;
ROBERTS, LM .
FEBS LETTERS, 1991, 292 (1-2) :275-278
[4]  
FARRIS JS, 1983, ADV CLADISTICS, P1
[5]   EVOLUTIONARY TREES FROM DNA-SEQUENCES - A MAXIMUM-LIKELIHOOD APPROACH [J].
FELSENSTEIN, J .
JOURNAL OF MOLECULAR EVOLUTION, 1981, 17 (06) :368-376
[6]  
Hannenhalli S., 1995, Proceedings of the Twenty-Seventh Annual ACM Symposium on the Theory of Computing, P178, DOI 10.1145/225058.225112
[7]  
Moret B M, 2001, Pac Symp Biocomput, P583
[8]  
Moret BME, 2001, LECT NOTES COMPUT SC, V2074, P1012
[9]   High-performance algorithm engineering for computational phylogenetics [J].
Moret, BME ;
Bader, DA ;
Warnow, T .
JOURNAL OF SUPERCOMPUTING, 2002, 22 (01) :99-110
[10]   THE NEIGHBOR-JOINING METHOD - A NEW METHOD FOR RECONSTRUCTING PHYLOGENETIC TREES [J].
SAITOU, N ;
NEI, M .
MOLECULAR BIOLOGY AND EVOLUTION, 1987, 4 (04) :406-425