Conductivities of three-layer live human skull

被引:186
作者
Akhtari, M
Bryant, HC
Marnelak, AN
Flynn, ER
Heller, L
Shih, JJ
Mandelkern, M
Matlachov, A
Ranken, DM
Best, ED
DiMauro, MA
Lee, RR
Sutherling, WW
机构
[1] Huntington Med Res Inst, Pasadena, CA USA
[2] Univ New Mexico, Dept Phys & Astron, Albuquerque, NM 87131 USA
[3] Univ New Mexico, Sch Med, Dept Neurol, Albuquerque, NM 87131 USA
[4] Univ New Mexico, Dept Neurosci, Albuquerque, NM 87131 USA
[5] Univ Calif Irvine, Dept Phys, Irvine, CA 92717 USA
[6] Huntington Mem Hosp, Epilepsy & Brain Mapping Program, Pasadena, CA USA
[7] Los Alamos Natl Lab, Div Phys, Los Alamos, NM 87545 USA
[8] VA Med Ctr, Dept Radiol, Albuquerque, NM USA
关键词
live human skull; conductivity; magnetoencephalography; electroencephalography;
D O I
10.1023/A:1014590923185
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Electrical conductivities of compact, spongiosum, and bulk layers of the live human skull were determined at varying frequencies and electric fields at room temperature using the four-electrode method. Current, at higher densities that occur in human cranium, was applied and withdrawn over the top and bottom surfaces of each sample and potential drop across different layers was measured. We used a model that considers variations in skull thicknesses to determine the conductivity of the tri-layer skull and its individual anatomical structures. The results indicate that the conductivities of the spongiform (16.2-41.1 milliS/m), the top compact (5.4-7.2 milliS/m) and lower compact (2.8-10.2 milliS/m) layers of the skull have significantly different and inhomogeneous conductivities. The conductivities of the skull layers are frequency dependent in the 10-90 Hz region and are non-ohmic in the 0.45-2.07 A/m(2) region. These current densities are much higher than those occurring in human brain.
引用
收藏
页码:151 / 167
页数:17
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