Terpeptin, a novel mammalian cell cycle inhibitor, produced by Aspergillus terreus 95F-1

被引：36

作者：

Kagamizono, T

Sakai, N

Arai, K

Kobinata, K

Osada, H

机构：

[1] INST PHYS & CHEM RES,WAKO,SAITAMA 35101,JAPAN

[2] TAISHO PHARMACEUT CO LTD,MED RES LABS,OMIYA,SAITAMA 330,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(97)00022-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Terpeptin, a novel peptide having cell cycle inhibitory activity, was isolated from the cultured broth of Aspergillus terreus 95F-1 and its structure was elucidated by spectral analyses: Terpeptin inhibited the cell cycle progression of mouse tsFT210 cells in the GuM phase with a minimum inhibitory concentration of 62.5 mu M. (C) 1997, Elsevier Science Ltd.

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页码：1223 / 1226

页数：4

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