Baroreflex function in hypertension: Consequences for antihypertensive therapy

被引：48

作者：

Grassi, G

Trevano, FQ

Seravalle, G

Scopelliti, F

Mancia, G

机构：

[1] Univ Milan, Med Clin, Osped San Gerardo Tinori,Ctr Interuniv Fisiol Cli, Dipartimento Med Clin Prevenz & Biotecnol Sanit, I-20052 Milan, Italy

[2] Ctr Auxol Italiano Piancavallo, Milan, Italy

来源：

PROGRESS IN CARDIOVASCULAR DISEASES | 2006年 / 48卷 / 06期

关键词：

D O I：

10.1016/j.pcad.2006.03.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Studies performed in experimental animal models of hypertension as well as in human hypertension have unequivocally shown that reflex cardiovascular control undergoes profound changes with high blood pressure and participates throughout direct and indirect mechanisms at the development and progression of hypertension-related target organ damage. This explains why investigation of the effects of antihypertensive drugs on neural cardiovascular control has a significant impact on hypertension treatment. This review will examine the main features of cardiovascular reflex control in hypertension and the effects of the different classes of antihypertensive drugs in uncomplicated and complicated hypertension. © 2006 Elsevier Inc. All rights reserved.

引用

页码：407 / 415

页数：9

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