One-pot synthesis of a polyrotaxane via selective threading of a PEI-b-PEG-b-PEI copolymer

被引：32

作者：

Choi, Hak Soo

Ooya, Tooru

Yui, Nobuhiko

机构：

[1] Japan Adv Inst Sci & Technol, Sch Mat Sci, Nomi, Ishikawa 9231292, Japan

[2] Japan Adv Inst Sci & Technol, Century COE Program 21, Nomi, Ishikawa 9231292, Japan

[3] Harvard Univ, Sch Med, Dept Med, Boston, MA 02215 USA

[4] Toyama Prefecrural Univ, Biotechnol Res Ctr, Dept Intelligent Design Syst Engn, Toyama 9390398, Japan

来源：

MACROMOLECULAR BIOSCIENCE | 2006年 / 6卷 / 06期

关键词：

block copolymers; cyclodextrin; polyrotaxanes; supramolecular structures;

D O I：

10.1002/mabi.200600024

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A functional polyrotaxane of a PEI-b-PEG-b-PEI copolymer is synthesized in aqueous solution in a one-pot sequence. To obtain a polyrotaxane with PEG-block-selective inclusion complexes, the solution pH of the polypseudorotaxane is lowered to 4,4 in the presence of 9-anthraldehyde (AN), which triggers the expulsion of the alpha-cyclodextrins (alpha-CDs) from the flank PEI chains.

引用

收藏

页码：420 / 424

页数：5

相关论文

共 32 条

[1] SIDE-CHAIN POLYROTAXANES WITH A TANDEM STRUCTURE-BASED ON CYCLODEXTRINS AND A POLYMETHACRYLATE MAIN-CHAIN [J].

BORN, M ;

RITTER, H .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1995, 34 (03) :309-311

[2] Design of rapidly assembling supramolecular systems responsive to synchronized stimuli [J].

Choi, HS ;

Yui, N .

PROGRESS IN POLYMER SCIENCE, 2006, 31 (02) :121-144

[3] Block-selective movement of α-cyclodextrins in polyrotaxanes of PEI-b-PEG-b-PEI copolymer [J].

Choi, HS ;

Lee, SC ;

Yamamoto, K ;

Yui, N .

MACROMOLECULES, 2005, 38 (23) :9878-9881

[4] Structural role of guest molecules in rapid and sensitive supramolecular assembling system based on β-cyclodextrin-conjugated poly(ε-lysine) [J].

Choi, HS ;

Takahashi, A ;

Ooya, T ;

Yui, N .

MACROMOLECULES, 2004, 37 (26) :10036-10041

[5] Dependence of polypseudorotaxane formation between cationic linear polyethylenimine and cyclodextrins [J].

Choi, HS ;

Ooya, T ;

Lee, SC ;

Sasaki, S ;

Kurisawa, M ;

Uyama, H ;

Yui, N .

MACROMOLECULES, 2004, 37 (18) :6705-6710

[6] pH-triggered assembling system using cooperative binding between cyclodextrin-conjugated poly(ε-lysine)s and anionic guest in aqueous media [J].

Choi, HS ;

Huh, KM ;

Ooya, T ;

Yui, N .

JOURNAL OF PHYSICAL CHEMISTRY B, 2004, 108 (23) :7646-7650

[7] Control of rapid phase transition induced by supramolecular complexation of β-cyclodextrin-conjugated poly(ε-lysine) with a specific guest [J].

Choi, HS ;

Ooya, T ;

Sasaki, S ;

Yui, N .

MACROMOLECULES, 2003, 36 (14) :5342-5347

[8] pH- and thermosensitive supramolecular assembling system:: Rapidly responsive properties of β-cyclodextrin-conjugated poly(ε-lysine) [J].

Choi, HS ;

Huh, KM ;

Ooya, T ;

Yui, N .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (21) :6350-6351

[9]

Choi HS, 2002, MACROMOL BIOSCI, V2, P298, DOI 10.1002/1616-5195(200208)2:6<298::AID-MABI298>3.0.CO

[10]

2-#

← 1 2 3 4 →