Continuous Flow Nitration of Benzaldehyde

被引：85

作者：

Kulkarni, Amol A. ^{[1
]}

Kalyani, Vishwanath S. ^{[1
]}

Joshi, Ramesh A. ^{[2
]}

Joshi, Rohini R. ^{[2
]}

机构：

[1] Natl Chem Lab, Chem Engn Div CEPD, Pune 411008, Maharashtra, India

[2] Natl Chem Lab, Div Organ Chem, Pune 411008, Maharashtra, India

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2009年 / 13卷 / 05期

关键词：

D O I：

10.1021/op900129w

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The nitration of benzaldebyde can be carried out in a safe manner in continuous mode using a microreactor system. Choice of a micromixer was seen to affect the performance of this two-phase reaction significantly The reaction time could he brought down to 2 min by increasing the reaction temperature and thereby taking advantage of higher heat transfer area. The simple T-micromixer is seen to be inefficient for two-phase reactions. Further scope of process intensification is also discussed.

引用

页码：999 / 1002

页数：4

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