Chemical composition and topology of poly(lactide-co-glycolide) revealed by pushing MALDI-TOF MS to its limit

被引：36

作者：

Huijser, Saskia ^{[1
]}

Staal, Bastiaan B. P. ^{[1
]}

Huang, Juan ^{[1
]}

Duchateau, Robbert ^{[1
]}

Koning, Cor E. ^{[1
]}

机构：

[1] Eindhoven Univ Technol, Polymer Chem Lab, Dept Chem & Chem Engn, NL-5600 MB Eindhoven, Netherlands

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 25期

关键词：

analytical methods; copolymerization; mass spectrometry; ring-opening polymerization; stannous octoate;

D O I：

10.1002/anie.200600594

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Graph Presented) Software developed in house in combination with a recently developed method of MALDI-TOF MS enable not only the elucidation of individual chain structures of poly(lactide-co-glycolide), a polymer used extensively in the medical sector, but a full characterization of this copolymer including even its chemical composition and topology (random, gradient, block (see figure), or alternating). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4104 / 4108

页数：5

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