Principles of opioid pharmacotherapy: Practical implications of basic mechanisms

被引:25
作者
Ferrante, FM
机构
[1] Cancer Pain and Symptom Mgmt. Prog., Hosp. of the Univ. of Pennsylvania, Philadelphia, PA
[2] Cancer Pain and Symptom Mgmt. Prog., Hosp. of the Univ. of Pennsylvania, Ravdin Courtyard Building, Philadelphia, PA 19104
关键词
pharmacotherapy; opioids; pain management; oral administration; parenteral administration;
D O I
10.1016/0885-3924(95)00201-4
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Opioids form the cornerstone of the pharmacologic armamentarium for the treatment of pain. Despite their long history of use, much confusion and misperception still surrounds their use. This short review will focus on pharmacodynamic and physiologic considerations in the clinical use of oral and parenteral opioids.
引用
收藏
页码:265 / 273
页数:9
相关论文
共 64 条
[1]  
BARASH P, 1980, ANESTHESIOLOGY, V53, pA109
[2]   SYNTHETIC ANALGESICS - STEREOCHEMICAL CONSIDERATIONS [J].
BECKETT, AH ;
CASY, AF .
JOURNAL OF PHARMACY AND PHARMACOLOGY, 1954, 6 (12) :986-1001
[3]   THE EFFECT OF DRUGS ON THE RESPIRATORY RESPONSE TO CARBON DIOXIDE [J].
BELLVILLE, JW ;
SEED, JC .
ANESTHESIOLOGY, 1960, 21 (06) :727-741
[4]   GASTROINTESTINAL PHARMACOLOGY [J].
BURKS, TF .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1976, 16 :15-31
[5]   A SELECTIVE DISTRIBUTION PATTERN OF DIFFERENT OPIATE RECEPTORS IN CERTAIN AREAS OF RAT-BRAIN AS REVEALED BY INVITRO AUTORADIOGRAPHY [J].
DUKA, T ;
SCHUBERT, P ;
WUSTER, M ;
STOIBER, R ;
HERZ, A .
NEUROSCIENCE LETTERS, 1981, 21 (02) :119-124
[6]  
ECKENHOFF JE, 1960, CLIN PHARMACOL THER, V1, P483
[7]  
FERRANTE FM, 1993, POSTOPERATIVE PAIN M, P145
[8]  
FIELDS HL, 1987, CENTRAL NERVOUS SYST, P99
[9]  
FLACKE JW, 1987, ANESTH ANALG, V66, P723
[10]   THE TREATMENT OF CANCER PAIN [J].
FOLEY, KM .
NEW ENGLAND JOURNAL OF MEDICINE, 1985, 313 (02) :84-95