An update on the oxazolidinone antibiotics

被引:5
作者
Abdel-Rahman, SM [1 ]
Kearns, GL [1 ]
机构
[1] Childrens Mercy Hosp, Kansas City, MO 64108 USA
关键词
D O I
10.1097/00006454-199912000-00015
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:1101 / 1102
页数:2
相关论文
共 15 条
[1]   Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant Gram-positive bacterial infections [J].
Brickner, SJ ;
Hutchinson, DK ;
Barbachyn, MR ;
Manninen, PR ;
Ulanowicz, DA ;
Garmon, SA ;
Grega, KC ;
Hendges, SK ;
Toops, DS ;
Ford, CW ;
Zurenko, GE .
JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (03) :673-679
[2]   In vitro activities of new oxazolidinone antimicrobial agents against enterococci [J].
Eliopoulos, GM ;
Wennersten, CB ;
Gold, HS ;
Moellering, RC .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (07) :1745-1747
[3]   Epidemiologic trends in nosocomial and community-acquired infections due to antibiotic-resistant gram-positive bacteria: The role of streptogramins and other newer compounds [J].
Jones, RN ;
Low, DE ;
Pfaller, MA .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 1999, 33 (02) :101-112
[4]   CLINICAL PHARMACOKINETICS IN INFANTS AND CHILDREN - A REAPPRAISAL [J].
KEARNS, GL ;
REED, MD .
CLINICAL PHARMACOKINETICS, 1989, 17 :29-67
[5]   The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin [J].
Lin, AH ;
Murray, RW ;
Vidmar, TJ ;
Marotti, KR .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (10) :2127-2131
[6]   In-vitro activity of 29 antimicrobial agents against penicillin-resistant and -intermediate isolates of Streptococcus pneumoniae [J].
Manzor, O ;
Pawlak, J ;
Saravolatz, L .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1999, 43 (01) :31-36
[7]   In vitro activities of oxazolidinones U-100592 and U-100766 against penicillin-resistant and cephalosporin-resistant strains of Streptococcus pneumoniae [J].
Mason, EO ;
Lamberth, LB ;
Kaplan, SL .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (04) :1039-1040
[8]   In vitro activities of an investigational quinolone, glycylcycline, glycopeptide, streptogramin, and oxazolidinone tested alone and in combinations against vancomycin-resistant Enterococcus faecium [J].
Mercier, RC ;
Penzak, SR ;
Rybak, MJ .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (11) :2573-2575
[9]   Comparative in vitro activities and postantibiotic effects of the oxazolidinone compounds eperezolid (PNU-100592) and linezolid (PNU-100766) versus vancomycin against Staphylococcus aureus, coagulase-negative staphylococci, Enterococcus faecalis, and Enterococcus faecium [J].
Rybak, MJ ;
Cappelletty, DM ;
Moldovan, T ;
Aeschlimann, JR ;
Kaatz, GW .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (03) :721-724
[10]   Serum inhibitory titers and serum bactericidal titers for human subjects receiving multiple doses of the antibacterial oxazolidinones eperezolid and linezolid [J].
Schaadt, RD ;
Batts, DH ;
DaleyYates, PT ;
Pawsey, SD ;
Stalker, DJ ;
Zurenko, GE .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 1997, 28 (04) :201-204