Enantioselective hydrogenation of methyl pyruvate over polymer-stabilized and supported iridium clusters

被引：33

作者：

Zuo, XB

Liu, HF ^{[1
]}

Yue, C

机构：

[1] Chinese Acad Sci, Polymer Chem Lab, Beijing 100080, Peoples R China

[2] Chinese Acad Sci, Inst Chem, China PetroChem Corp, Beijing 100080, Peoples R China

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 1999年 / 147卷 / 1-2期

关键词：

iridium; methyl pyruvate; cinchonidine; enantioselective hydrogenation; rate-promoting effect;

D O I：

10.1016/S1381-1169(99)00129-6

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The enantioselective hydrogenation of methyl pyruvate was studied over finely dispersed polyvinylpyrrolidone-stabilized iridium (PVP-Ir) and the corresponding alumina-supported iridium cluster (Al2O3-Ir) modified with cinchonidine. It was found that the modifier, apart from inducing enantioselectivity, has a considerable rate-promoting effect on this reaction with the average rate increased by a actor of 2-3.5 over both the two kinds of catalysts. Favorable reaction parameters were 283 K, 4.0 MPa and alcohols or acetic acid as solvents. Similar to what had been reported in Pt/cinchona system, the highest value of the enantiomeric excess (34.1%) was obtained in acetic acid, accompanied by a marked enhancement of the reaction rate. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：63 / 72

页数：10

共 54 条

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