Occupational and environmental radiation and cancer

被引:42
作者
Boice, JD [1 ]
Lubin, JH [1 ]
机构
[1] US NATL CANC INST, DIV CANC EPIDEMIOL & GENET, EPIDEMIOL & BIOSTAT PROGRAM, BETHESDA, MD USA
关键词
cancer; environment; ionizing radiation; leukemia; occupation; radon;
D O I
10.1023/A:1018496919324
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Epidemiologic evidence on the relation between occupational and environmental radiation and cancer is reviewed, Studies of pioneering radiation workers, underground miners? and radium dial painters revealed excess cancer deaths and contributed to the setting of radiation protection standards and to theories of carcinogenesis, Occupational exposures today are generally much lower than in the past, thus any associated increases in cancer will be difficult to detect. Pooling investigations of these more recently exposed workers, however, has the potential to validate current estimates of risk used in radiation protection. New information on the effects of chronic radiation exposure also map come from studies in the former Soviet Union of Chernobyl clean-up workers and of workers at the Mayak nuclear facilities. Studies of environmental radiation exposures, other than radon, are largely inconclusive, due mainly to the difficulties in detecting the low risks associated with low dose exposures. Thyroid cancer, however, has been linked to environmental radiation from the Chernobyl accident and from nuclear weapons tests, Low-level radiation released during normal operations at nuclear plants has not been found to increase cancer rates in surrounding populations, Radon, a human carcinogen, is the most ubiquitous exposure to human populations; remediating high residential-radon levels is recommended, recognizing that the exposure can never be removed completely because it occurs naturally.
引用
收藏
页码:309 / 322
页数:14
相关论文
共 157 条
[21]  
BOICE JD, 1984, RAD CARCINOGENESIS E, P1
[22]   MECHANISTIC CONSIDERATIONS ON THE DOSE-RATE LET DEPENDENCE OF ONCOGENIC TRANSFORMATION BY IONIZING-RADIATIONS [J].
BRENNER, DJ ;
HALL, EJ ;
RANDERSPEHRSON, G ;
MILLER, RC .
RADIATION RESEARCH, 1993, 133 (03) :365-369
[23]   THE SIGNIFICANCE OF DOSE-RATE IN ASSESSING THE HAZARDS OF DOMESTIC RADON EXPOSURE [J].
BRENNER, DJ .
HEALTH PHYSICS, 1994, 67 (01) :76-79
[24]  
BURKHART W, 1994, SCI TOTAL ENVIRON, V142, P1
[25]   MORTALITY AND CANCER FREQUENCY AMONG MILITARY NUCLEAR TEST (SMOKY) PARTICIPANTS, 1957 THROUGH 1979 [J].
CALDWELL, GG ;
KELLEY, D ;
ZACK, M ;
FALK, H ;
HEATH, CW .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1983, 250 (05) :620-624
[26]   EFFECTS OF LOW-DOSES AND LOW-DOSE RATES OF EXTERNAL IONIZING-RADIATION - CANCER MORTALITY AMONG NUCLEAR INDUSTRY WORKERS IN 3 COUNTRIES [J].
CARDIS, E ;
GILBERT, ES ;
CARPENTER, L ;
HOWE, G ;
KATO, I ;
ARMSTRONG, BK ;
BERAL, V ;
COWPER, G ;
DOUGLAS, A ;
FIX, J ;
FRY, SA ;
KALDOR, J ;
LAVE, C ;
SALMON, L ;
SMITH, PG ;
VOELZ, GL ;
WIGGS, LD .
RADIATION RESEARCH, 1995, 142 (02) :117-132
[27]  
CARDIS E, 1996, RADIOLOGICAL CONSEQU
[28]   COMBINED ANALYSIS OF MORTALITY IN 3 UNITED-KINGDOM NUCLEAR INDUSTRY WORKFORCES, 1946-1988 [J].
CARPENTER, L ;
HIGGINS, C ;
DOUGLAS, A ;
FRASER, P ;
BERAL, V ;
SMITH, P .
RADIATION RESEARCH, 1994, 138 (02) :224-238
[29]   TEST OF THE LINEAR-NO THRESHOLD THEORY OF RADIATION CARCINOGENESIS FOR INHALED RADON DECAY PRODUCTS [J].
COHEN, BL .
HEALTH PHYSICS, 1995, 68 (02) :157-174
[30]  
CONARD RA, 1984, RAD CARCINOGENESIS E, P57