Responsibilities of Health Care Professionals in Counseling and Educating PatientsWith Incurable Neurological Diseases Regarding "Stem Cell Tourism" Caveat Emptor

被引:33
作者
Bowman, Michelle [1 ]
Racke, Michael [1 ]
Kissel, John [2 ,3 ,4 ]
Imitola, Jaime [1 ,5 ]
机构
[1] Ohio State Univ, Wexner Med Ctr, Multiple Sclerosis Ctr, Columbus, OH 43321 USA
[2] Ohio State Univ, Wexner Med Ctr, Dept Neurol, Div Neuromuscular Med, Columbus, OH 43321 USA
[3] Ohio State Univ, Wexner Med Ctr, Dept Neurol, Columbus, OH 43321 USA
[4] Ohio State Univ, Wexner Med Ctr, Dept Neurosci, Columbus, OH 43321 USA
[5] Ohio State Univ, Wexner Med Ctr, Div Neuroimmunol & Multiple Sclerosis, Lab Neural Stem Cells & Funct Neurogenet, Columbus, OH 43321 USA
关键词
AMYOTROPHIC-LATERAL-SCLEROSIS; MULTIPLE-SCLEROSIS; TRANSPLANTATION; THERAPIES;
D O I
10.1001/jamaneurol.2015.1891
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
"Stem cell tourism" is a rising Internet-based industry that aims to offer unproven procedures to patients with incurable diseases. This unregulated activity is reaching the neurologist's office as well as across the world, as patients request information or clearance for such procedures. Herein, we posit the need for medical societies and licensing boards to bring this issue to the forefront of neurology because it has the potential to affect patient care with risk of morbidity and mortality, as well as to undermine public confidence in legitimate stem cell research for incurable neurological diseases such as multiple sclerosis and amyotrophic lateral sclerosis.
引用
收藏
页码:1342 / 1345
页数:4
相关论文
共 26 条
[1]
Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient [J].
Amariglio, Ninette ;
Hirshberg, Abraham ;
Scheithauer, Bernd W. ;
Cohen, Yoram ;
Loewenthal, Ron ;
Trakhtenbrot, Luba ;
Paz, Nurit ;
Koren-Michowitz, Maya ;
Waldman, Dalia ;
Leider-Trejo, Leonor ;
Toren, Amos ;
Constantini, Shlomi ;
Rechavi, Gideon .
PLOS MEDICINE, 2009, 6 (02) :221-231
[2]
Charo A, STEM CELLS SAVE HOPE
[3]
Brain atrophy after immunoablation and stem cell transplantation in multiple sclerosis [J].
Chen, J. T. ;
Collins, D. L. ;
Atkins, H. L. ;
Freedman, M. S. ;
Galal, A. ;
Arnold, D. L. .
NEUROLOGY, 2006, 66 (12) :1935-1937
[4]
Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study [J].
Connick, Peter ;
Kolappan, Madhan ;
Crawley, Charles ;
Webber, Daniel J. ;
Patani, Rickie ;
Michell, Andrew W. ;
Du, Ming-Qing ;
Luan, Shi-Lu ;
Altmann, Daniel R. ;
Thompson, Alan J. ;
Compston, Alastair ;
Scott, Michael A. ;
Miller, David H. ;
Chandran, Siddharthan .
LANCET NEUROLOGY, 2012, 11 (02) :150-156
[5]
Cyranoski D, 2014, NATURE, V507, P283
[6]
Cellular transplants in China: Observational study from the largest human experiment in chronic spinal cord injury [J].
Dobkin, BH ;
Curt, A ;
Guest, J .
NEUROREHABILITATION AND NEURAL REPAIR, 2006, 20 (01) :5-13
[7]
Intraspinal neural stem cell transplantation in amyotrophic lateral sclerosis: Phase 1 trial outcomes [J].
Feldman, Eva L. ;
Boulis, Nicholas M. ;
Hur, Junguk ;
Johe, Karl ;
Rutkove, Seward B. ;
Federici, Thais ;
Polak, Meraida ;
Bordeau, Jane ;
Sakowski, Stacey A. ;
Glass, Jonathan D. .
ANNALS OF NEUROLOGY, 2014, 75 (03) :363-373
[8]
Characterization of Autologous Mesenchymal Stem Cell-Derived Neural Progenitors as a Feasible Source of Stem Cells for Central Nervous System Applications in Multiple Sclerosis [J].
Harris, Violaine K. ;
Faroqui, Raihan ;
Vyshkina, Tamara ;
Sadiq, Saud A. .
STEM CELLS TRANSLATIONAL MEDICINE, 2012, 1 (07) :536-547
[9]
Concise Review: Workshop Review: Understanding and Assessing the Risks of Stem Cell-Based Therapies [J].
Heslop, James A. ;
Hammond, Thomas G. ;
Santeramo, Ilaria ;
Piella, Agnes Tort ;
Hopp, Isabel ;
Zhou, Jing ;
Baty, Roua ;
Graziano, Enrique I. ;
Marco, Bernabe Proto ;
Caron, Alexis ;
Skold, Patrik ;
Andrews, Peter W. ;
Baxter, Melissa A. ;
Hay, David C. ;
Hamdam, Junnat ;
Sharpe, Michaela E. ;
Patel, Sara ;
Jones, David R. ;
Reinhardt, Jens ;
Danen, Erik H. J. ;
Ben-David, Uri ;
Stacey, Glyn ;
Bjorquist, Petter ;
Piner, Jacqueline ;
Mills, John ;
Rowe, Cliff ;
Pellegrini, Giovanni ;
Sethu, Swaminathan ;
Antoine, Daniel J. ;
Cross, Michael J. ;
Murray, Patricia ;
Williams, Dominic P. ;
Kitteringham, Neil R. ;
Goldring, Chris E. P. ;
Park, B. Kevin .
STEM CELLS TRANSLATIONAL MEDICINE, 2015, 4 (04) :389-400
[10]
Therapeutic Hope, Spiritual Distress, and the Problem of Stem Cell Tourism [J].
Hyun, Insoo .
CELL STEM CELL, 2013, 12 (05) :505-507