About GATA3, HNF3A, and XBP1, three genes co-expressed with the oestrogen receptor-α gene (ESRI) in breast cancer

被引：109

作者：

Lacroix, M ^{[1
]}

Leclercq, G ^{[1
]}

机构：

[1] Free Univ Brussels, Inst Jules Bordet, Lab Jean Claude Heuson Cancerol Mammaire, B-1000 Brussels, Belgium

来源：

MOLECULAR AND CELLULAR ENDOCRINOLOGY | 2004年 / 219卷 / 1-2期

关键词：

breast cancer; oestrogen receptor-alpha; GATA-3; HNF-3; alpha; XBP-l; TFFI;

D O I：

10.1016/j.mce.2004.02.021

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In breast tumours and breast cancer cell (BCC) lines, microarray analyses have revealed that a series of genes are expressed in close association with the oestrogen receptor-alpha (ER-alpha) gene, ESR1. Three of them, GATA3, HNF3A (also known as FOXA1), and XBP1 encode transcription factors. Here, we present these factors and we discuss their potential involvement in the ER-alpha-mediated actions in BCC. We notably show the relations that exist, or that might exist, between these factors and the oestrogen-inducible trefoil factor TFF1. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

引用

页码：1 / 7

页数：7

共 68 条

[1] Transcription factor GATA-6 activates expression of gastroprotective trefoil genes TFF1 and TFF2 [J].

Al-azzeh, ED ;

Fegert, P ;

Blin, N ;

Gött, P .

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 2000, 1490 (03) :324-332

[2] Transcriptional synergism on the pS2 gene promoter between a p160 coactivator and estrogen receptor-α depends on the coactivatior subtype, the type of estrogen response element, and the promoter context [J].

Barkhem, T ;

Haldosén, LA ;

Gustafsson, JÅ ;

Nilsson, S .

MOLECULAR ENDOCRINOLOGY, 2002, 16 (11) :2571-2581

[3] Hepatocyte nuclear factor 3 (winged helix domain) activates trefoil factor gene TFF1 through a binding motif adjacent to the TATAA box [J].

Beck, S ;

Sommer, P ;

Silva, ED ;

Blin, N ;

Gött, P .

DNA AND CELL BIOLOGY, 1999, 18 (02) :157-164

[4] Gene expression profiling of primary breast carcinomas using arrays of candidate genes [J].

Bertucci, F ;

Houlgatte, R ;

Benziane, A ;

Granjeaud, S ;

Adélaïde, J ;

Tagett, R ;

Loriod, B ;

Jacquemier, J ;

Viens, P ;

Jordan, B ;

Birnbaum, D ;

Nguyen, C .

HUMAN MOLECULAR GENETICS, 2000, 9 (20) :2981-2991

[5] The trefoil factor 1 participates in gastrointestinal cell differentiation by delaying G1-S phase transition and reducing apoptosis [J].

Bossenmeyer-Pourié, C ;

Kannan, R ;

Ribieras, S ;

Wendling, C ;

Stoll, I ;

Thim, L ;

Tomasetto, C ;

Rio, MC .

JOURNAL OF CELL BIOLOGY, 2002, 157 (05) :761-770

[6]

Bouras T, 2002, CANCER RES, V62, P1289

[7] Liver-enriched transcription factors and hepatocyte differentiation [J].

Cereghini, S .

FASEB JOURNAL, 1996, 10 (02) :267-282

[8] Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: Phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression [J].

Chen, CH ;

Zhang, DH ;

LaPorte, JM ;

Ray, A .

JOURNAL OF IMMUNOLOGY, 2000, 165 (10) :5597-5605

[9] Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome [J].

Cirillo, LA ;

McPherson, CE ;

Bossard, P ;

Stevens, K ;

Cherian, S ;

Shim, EY ;

Clark, KL ;

Burley, SK ;

Zaret, KS .

EMBO JOURNAL, 1998, 17 (01) :244-254

[10] CO-CRYSTAL STRUCTURE OF THE HNF-3/FORK HEAD DNA-RECOGNITION MOTIF RESEMBLES HISTONE-H5 [J].

CLARK, KL ;

HALAY, ED ;

LAI, ES ;

BURLEY, SK .

NATURE, 1993, 364 (6436) :412-420

← 1 2 3 4 5 6 7 →