Structural Ties between Cholesterol Transport and Morphogen Signaling

被引:39
作者
Bazan, J. Fernando [1 ,2 ]
de Sauvage, Frederic J. [3 ]
机构
[1] Genentech Inc, Dept Prot Engn, San Francisco, CA 94080 USA
[2] Genentech Inc, Dept Biol Struct, San Francisco, CA 94080 USA
[3] Genentech Inc, Dept Mol Biol, San Francisco, CA 94080 USA
关键词
BINDING PROTEIN; DOMAINS; REVEALS;
D O I
10.1016/j.cell.2009.09.006
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:1055 / 1056
页数:2
相关论文
共 11 条
[1]   The Extracellular Domain of Smoothened Regulates Ciliary Localization and Is Required for High-Level Hh Signaling [J].
Aanstad, Pia ;
Santos, Nicole ;
Corbit, Kevin C. ;
Scherz, Paul J. ;
Trinh, Le A. ;
Salvenmoser, Willi ;
Huisken, Jan ;
Reiter, Jeremy F. ;
Stainier, Didier Y. R. .
CURRENT BIOLOGY, 2009, 19 (12) :1034-1039
[2]   The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling [J].
Bosanac, Ivan ;
Maun, Henry R. ;
Scales, Suzie J. ;
Wen, Xiaohui ;
Lingel, Andreas ;
Bazan, J. Fernando ;
de Sauvage, Frederic J. ;
Hymowitz, Sarah G. ;
Lazarus, Robert A. .
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2009, 16 (07) :691-U28
[3]   New class of blue animal pigments based on Frizzled and Kringle protein domains [J].
Bulina, ME ;
Lukyanov, KA ;
Yampolsky, IV ;
Chudakov, DM ;
Staroverov, DB ;
Shcheglov, AS ;
Gurskaya, NG ;
Lukyanov, S .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (42) :43367-43370
[4]   Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains [J].
Dann, CE ;
Hsieh, JC ;
Rattner, A ;
Sharma, D ;
Nathans, J ;
Leahy, DJ .
NATURE, 2001, 412 (6842) :86-90
[5]   The Hedgehog Signaling Pathway: Where Did It Come From? [J].
Hausmann, George ;
von Mering, Christian ;
Basler, Konrad .
PLOS BIOLOGY, 2009, 7 (06)
[6]   Searching protein structure databases with DaliLite v.3 [J].
Holm, L. ;
Kaariainen, S. ;
Rosenstrom, P. ;
Schenkel, A. .
BIOINFORMATICS, 2008, 24 (23) :2780-2781
[7]   Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol [J].
Kwon, Hyock Joo ;
Abi-Mosleh, Lina ;
Wang, Michael L. ;
Deisenhofer, Johann ;
Goldstein, Joseph L. ;
Brown, Michael S. ;
Infante, Rodney E. .
CELL, 2009, 137 (07) :1213-1224
[8]   Activation of pheromone-sensitive neurons is mediated by conformational activation of pheromone-binding protein [J].
Laughlin, John D. ;
Ha, Tal Soo ;
Jones, David N. M. ;
Smith, Dean P. .
CELL, 2008, 133 (07) :1255-1265
[9]   Crystal structure of chicken riboflavin-binding protein [J].
Monaco, HL .
EMBO JOURNAL, 1997, 16 (07) :1475-1483
[10]   Protein homology detection by HMM-HMM comparison [J].
Söding, J .
BIOINFORMATICS, 2005, 21 (07) :951-960