90K (Mac-2 BP) in human milk

被引：34

作者：

DOstilio, N

Sabatino, G

Natoli, C

Ullrich, A

Iacobelli, S

机构：

[1] UNIV G DANNUNZIO,FAC MED & CHIRURG,CATTEDRA ONCOL MED,I-66100 CHIETI,ITALY

[2] UNIV G DANNUNZIO,CATTEDRA NEONATOL,I-66100 CHIETI,ITALY

[3] MAX PLANCK INST BIOCHEM,DEPT MOLEC BIOL,W-8033 MARTINSRIED,GERMANY

来源：

CLINICAL AND EXPERIMENTAL IMMUNOLOGY | 1996年 / 104卷 / 03期

关键词：

newborn; host defence; gastrointestinal infection;

D O I：

10.1046/j.1365-2249.1996.40745.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Human 90K, also known as Mac-2 binding protein (Mac-2 BP), is a secreted glycoprotein which is widely expressed, binds to the human macrophage-associated lectin Mac-2, and may have a role in host defence. We have measured the concentrations of 90K in human breast milk from eight healthy mothers delivering mature healthy infants after full-term pregnancy using a specific immunoenzymatic assay. Maximal 90K concentrations were observed on days 2-3 post-partum, and ranged from 13.4 to 79.2 mu g/ml. The concentrations of 90K in the milk had no correlation with those in the maternal blood.

引用

页码：543 / 546

页数：4

共 23 条

[1] MOLECULAR-CLONING OF A HUMAN MACROPHAGE LECTIN SPECIFIC FOR GALACTOSE [J].