Overcoming insulin resistance with CNTF

被引：16

作者：

Ahima, RS ^{[1
]}

机构：

[1] Univ Penn, Sch Med, Dept Med, Div Endocrinol Diabet & Metab, Philadelphia, PA 19104 USA

来源：

NATURE MEDICINE | 2006年 / 12卷 / 05期

关键词：

D O I：

10.1038/nm0506-511

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ciliary neurotrophic factor (CNTF) enhances fatty-acid oxidation in muscle and reduces insulin resistance in obese, diabetic mice. Because skeletal muscle is the major site of insulin-mediated glucose uptake, this action of CNTF could benefit individuals with diabetes.

引用

页码：511 / 512

页数：3

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