Cytogenetic abnormalities in multiple myeloma

被引：20

作者：

Fonseca, R

Coignet, LJA

Dewald, GW

机构：

[1] Mayo Clin & Mayo Fdn, Dept Hematol & Internal Med, Rochester, MN 55905 USA

[2] Mayo Clin & Mayo Fdn, Dept Lab Med & Pathol, Rochester, MN 55905 USA

[3] Mayo Clin & Mayo Grad Sch Med, Rochester, MN 55901 USA

[4] Loyola Univ, Med Ctr, Dept Med, Cardinal Bernardin Canc Ctr, Maywood, IL 60153 USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 1999年 / 13卷 / 06期

关键词：

D O I：

10.1016/S0889-8588(05)70119-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

There is an increasing understanding that chromosomal abnormalities play a major role in the pathogenesis of multiple myeloma. Furthermore, they seem to predict the clinical outcome of patients according to the specific abnormalities detected. It is Likely that in the future, knowledge of the cytogenetic composition will be an integral part of the evaluation of myeloma patients.

引用

页码：1169 / +

页数：13

共 47 条

[1] THE C-MYC ONCOGENE DRIVEN BY IMMUNOGLOBULIN ENHANCERS INDUCES LYMPHOID MALIGNANCY IN TRANSGENIC MICE [J].