Polymer chain models of DNA and chromatin

被引：94

作者：

Langowski, J. ^{[1
]}

机构：

[1] German Canc Res Ctr, Div Biophys Macromol, D-69120 Heidelberg, Germany

来源：

EUROPEAN PHYSICAL JOURNAL E | 2006年 / 19卷 / 03期

关键词：

D O I：

10.1140/epje/i2005-10067-9

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Many properties of the genome in the cell nucleus can be understood by modeling DNA and chromatin as a flexible polymer chain. This article introduces in to current models for such a coarse-grained description and reviews some recent results from our own group. Examples given are the unrolling of DNA from the histone core and the response of the 30 nm chromatin fiber to mechanical stretching.

引用

页码：241 / 249

页数：9

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