Preparation of surface-engineered elastin/lamin nerve guide tubes of poly(lactic acid)/poly(ethylene vinyl acetate)

被引：2

作者：

Chandy, T

Rao, GHR

机构：

[1] Univ Minnesota, Dept Cardiol, Minneapolis, MN 55455 USA

[2] Univ Minnesota, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA

来源：

JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS | 2002年 / 17卷 / 03期

关键词：

D O I：

10.1106/088391102026102

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In this study, a spray coating technique was used to prepare poly(lactic acid) (PLA) tubes. To improve the flexibility of these devices, an elastomeric polymer, poly(ethylene vinyl acetate) (PEVAc), was added to the PLA. The PLA/PEVAc tubes were further surface modified with elastin and laminin via carbodiimide and glutaraldehyde treatment. This study evaluated the surface graft matrix components (elastin and laminin) on PLA/PEVAc tubes as a method for regenerating biointeractive materials for nerve growth and tissue engineering.

引用

页码：183 / 194

页数：12

共 33 条

[1] NERVE CABLES FORMED IN SILICONE CHAMBERS RECONSTITUTE A PERINEURIAL BUT NOT A VASCULAR ENDONEURIAL PERMEABILITY BARRIER [J].