Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso -: art. no. 10

被引：9

作者：

Müller, O

Traore, C

Kouyate, B

机构：

[1] Univ Heidelberg, Dept Trop Hyg & Publ Hlth, Heidelberg, Germany

[2] Ctr Rech Sante Nouna, Nouna, Burkina Faso

来源：

MALARIA JOURNAL | 2004年 / 3卷 / 1期

关键词：

D O I：

10.1186/1475-2875-3-10

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported. Of 28 children treated with a standard single dose of pyrimethamine-sulfadoxine and followed-up over 14 days, only one Late Treatment Failure and four Late Parasitological Failures were observed, all with low-grade parasitaemia. In this area of very restricted use of pyrimethamine-sulfadoxine, the drug appears to be still sufficiently effective in the treatment of malaria. These findings provide further evidence for the justification of continued use of pyrimethamine-sulfadoxine as a second-line treatment for malaria in Burkina Faso.

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页数：3

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