Use of γ-carboxy-α,β-unsaturated aldehydes as synthetic equivalents of β,γ-unsaturated aldehydes in a novel stereoselective approach to diketides

被引：50

作者：

Hughes, G ^{[1
]}

Lautens, M ^{[1
]}

Wen, C ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 02期

关键词：

D O I：

10.1021/ol991170n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A two-step aldol/Pd-catalyzed formate reduction sequence allows for convenient, stereoselective access to products of great potential in synthetic approaches to polyketides, A novel diastereoselective Pd-catalyzed formate reduction of allylic acetates is reported.

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页码：107 / 110

页数：4

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