PDGF signaling in cells and mice

被引：336

作者：

Tallquist, M

Kazlauskas, A

机构：

[1] Harvard Univ, Sch Med, Schepens Eye Res Inst, Boston, MA 02114 USA

[2] Univ Texas, SW Med Ctr, Dept Mol Biol, Dallas, TX 75390 USA

来源：

CYTOKINE & GROWTH FACTOR REVIEWS | 2004年 / 15卷 / 04期

关键词：

PDGF signaling; growth factor; tissue culture; mouse models;

D O I：

10.1016/j.cytogfr.2004.03.003

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Since its discovery over three decades ago, platelet-derived growth factor (PDGF) has been a model system for learning how growth factors regulate biological processes. For the first several decades investigators used cells grown in tissue culture. More recently, PDGF signaling has also been investigated in mice. This review outlines the advances in these two systems, and highlights some of the directions for future investigation. (C) 2004 Elsevier Ltd. All rights reserved.

引用

收藏

页码：205 / 213

页数：9

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