Comparison of eight published static finite element models of the intact lumbar spine: Predictive power of models improves when combined together

被引：398

作者：

Dreischarf, M. ^{[1
]}

Zander, T. ^{[1
]}

Shirazi-Adl, A. ^{[2
]}

Puttlitz, C. M. ^{[8
]}

Adam, C. J. ^{[9
]}

Chen, C. S. ^{[3
]}

Goel, V. K. ^{[4
,5
,6
]}

Kiapour, A. ^{[4
,5
,6
]}

Kim, Y. H. ^{[7
]}

Labus, K. M. ^{[8
]}

Little, J. P. ^{[9
]}

Park, W. M. ^{[7
]}

Wang, Y. H. ^{[3
]}

Wilke, H. J. ^{[10
]}

Rohlmann, A. ^{[1
]}

Schmidt, H. ^{[1
,10
]}

机构：

[1] Charite, Julius Wolff Inst, D-13353 Berlin, Germany

[2] Ecole Polytech, Dept Mech Engn, Div Appl Mech, Montreal, PQ H3C 3A7, Canada

[3] Natl Yang Ming Univ, Dept Phys Therapy & Assist Technol, Taipei 112, Taiwan

[4] Univ Toledo, Coll Engn, Dept Bioengn, Toledo, OH USA

[5] Univ Toledo, Coll Engn, Dept Orthopaed Surg, Toledo, OH USA

[6] Univ Toledo, Coll Med, Toledo, OH USA

[7] Kyung Hee Univ, Dept Mech Engn, Yongin 446701, South Korea

[8] Colorado State Univ, Orthopaed Bioengn Res Lab, Ft Collins, CO 80523 USA

[9] Queensland Univ Technol, Inst Hlth & Biomed Innovat, Paediat Spine Res Grp, Brisbane, Qld 4001, Australia

[10] Inst Orthopaed Res & Biomech, Ulm, Germany

来源：

JOURNAL OF BIOMECHANICS | 2014年 / 47卷 / 08期

关键词：

Validation; Finite element model; Lumbar spine; Verification; Sensitivity; Inter-subject variability; Predictive power; QUANTITATIVE 3-DIMENSIONAL ANATOMY; INTRADISCAL PRESSURE; INTERVERTEBRAL DISCS; MECHANICAL-BEHAVIOR; STRESS-ANALYSIS; MATERIAL SENSITIVITY; STEPWISE REDUCTION; MOTION SEGMENT; AXIAL ROTATION; VALIDATION;

D O I：

10.1016/j.jbiomech.2014.04.002

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 [生物物理学];

摘要：

Finite element (FE) model studies have made important contributions to our understanding of functional biomechanics of the lumbar spine. However, if a model is used to answer clinical and biomechanical questions over a certain population, their inherently large inter-subject variability has to be considered. Current FE model studies, however, generally account only for a single distinct spinal geometry with one set of material properties. This raises questions concerning their predictive power, their range of results and on their agreement with in vitro and in vivo values. Eight well-established FE models of the lumbar spine (L1-5) of different research centers around the globe were subjected to pure and combined loading modes and compared to in vitro and in vivo measurements for intervertebral rotations, disc pressures and facet joint forces. Under pure moment loading, the predicted L1-5 rotations of almost all models fell within the reported in vitro ranges, and their median values differed on average by only 2 degrees for flexion-extension, 1 degrees for lateral bending and 5 degrees for axial rotation. Predicted median facet joint forces and disc pressures were also in good agreement with published median in vitro values. However, the ranges of predictions were larger and exceeded those reported in vitro, especially for the facet joint forces. For all combined loading modes, except for flexion, predicted median segmental intervertebral rotations and disc pressures were in good agreement with measured in vivo values. In light of high inter-subject variability, the generalization of results of a single model to a population remains a concern. This study demonstrated that the pooled median of individual model results, similar to a probabilistic approach, can be used as an improved predictive tool in order to estimate the response of the lumbar spine. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：1757 / 1766

页数：10

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