Thrombophilia and recurrent pregnancy loss

被引：13

作者：

Carp, Howard J. A. ^{[2
]}

机构：

[1] Tel Aviv Univ, IL-69978 Ramat Aviv, Israel

[2] Chaim Sheba Med Ctr, Dept Obstet & Gynecol, IL-52621 Tel Hashomer, Israel

来源：

OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA | 2006年 / 33卷 / 03期

关键词：

D O I：

10.1016/j.ogc.2006.05.012

中图分类号：

R71 [妇产科学];

学科分类号：

100211 [妇产科学];

摘要：

Thrombophilias seem to be associated with, and may even cause some cases of pregnancy loss. However, the role of treatment remains to be determined, as currently there is little good evidence of effect. There is a serious ethical dilemma, as to whether treatment that may be effective should be denied to patients with numerous prior pregnancy losses. It is strongly suggested that when treatment fails, the embryo should be karyotyped to exclude chromosomal aberrations.

引用

页码：429 / +

页数：15

共 90 条

[1]

How strong is the association between maternal thrombophilia and adverse pregnancy outcome? A systematic review [J].

Alfirevic, Z ;

Roberts, D ;

Martlew, V .

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2002, 101 (01) :6-14

[2]

*AM COLL OBST GYN, 2001, ACOG PRACTICE B, V24, P1

[3]

Arias F, 1998, J Matern Fetal Med, V7, P277

[4]

Inhibitory effects of low molecular weight heparin on mediator release by mast cells: preferential inhibition of cytokine production and mast cell dependent cutaneous inflammation [J].

Baram, D ;

Rashkovsky, M ;

Hershkoviz, R ;

Drucker, I ;

Reshef, T ;

Ben-Shitrit, S ;

Mekori, YA .

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 1997, 110 (03) :485-491

[5]

Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles [J].

Barry, OP ;

Pratico, D ;

Lawson, JA ;

FitzGerald, GA .

JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (09) :2118-2127

[6]

Use of antithrombotic agents during pregnancy [J].

Bates, SA ;

Greer, IA ;

Hirsh, J ;

Ginsberg, JS .

CHEST, 2004, 126 (03) :627S-644S

[7]

Plasma tumor necrosis factor α levels and the-238*A promoter polymorphism in patients with antiphospholipid syndrome [J].

Bertolaccini, ML ;

Atsumi, T ;

Lanchbury, JS ;

Caliz, AR ;

Katsumata, K ;

Vaughan, RW ;

Kondeatis, E ;

Khamashta, MA ;

Kolke, T ;

Hughes, GRV .

THROMBOSIS AND HAEMOSTASIS, 2001, 85 (02) :198-203

[8]

Brenner B, 2000, THROMB HAEMOSTASIS, V83, P693

[9]

Efficacy and safety of two doses of enoxaparin in women with thrombophilia and recurrent pregnancy loss: the LIVE-ENOX study [J].

Brenner, B ;

Hoffman, R ;

Carp, H ;

Dulitsky, M ;

Younis, J .

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2005, 3 (02) :227-229

[10]

Circulating microparticles: a marker of procoagulant state in normal pregnancy and pregnancy complicated by preeclampsia or intrauterine growth restriction [J].

Bretelle, F ;

Sabatier, F ;

Desprez, D ;

Camoin, L ;

Grunebaum, L ;

Combes, V ;

D'Ercole, C ;

Dignat-George, F .

THROMBOSIS AND HAEMOSTASIS, 2003, 89 (03) :486-492

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