Use of capsule endoscopy in patients with Crohn's disease in Japan: A multicenter survey

被引：70

作者：

Esaki, Motohiro ^{[1
]}

Matsumoto, Takayuki ^{[1
,7
]}

Watanabe, Kenji ^{[2
]}

Arakawa, Tetsuo ^{[2
]}

Naito, Yuji ^{[3
]}

Matsuura, Minoru ^{[4
]}

Nakase, Hiroshi ^{[4
]}

Hibi, Toshifumi ^{[5
]}

Matsumoto, Takayuki ^{[1
,7
]}

Nouda, Sadaharu ^{[8
]}

Higuchi, Kazuhide ^{[8
]}

Ohmiya, Naoki ^{[9
]}

Goto, Hidemi ^{[9
]}

Kurokawa, Sei ^{[10
]}

Motoya, Satoshi ^{[10
]}

Watanabe, Mamoru ^{[6
]}

机构：

[1] Kyushu Univ, Grad Sch Med Sci, Dept Med & Clin Sci, Fukuoka 8128582, Japan

[2] Osaka City Univ, Grad Sch Med, Dept Gastroenterol, Osaka 558, Japan

[3] Kyoto Prefectural Univ Med, Kyoto 602, Japan

[4] Kyoto Univ, Grad Sch Med, Dept Gastroenterol & Hepatol, Kyoto, Japan

[5] Keio Univ, Sch Med, Dept Internal Med, Div Gastroenterol & Hepatol, Tokyo 108, Japan

[6] Tokyo Med & Dent Univ, Sch Med, Dept Gastroenterol, Tokyo 113, Japan

[7] Hyogo Coll Med, Dept Internal Med, Div Lower Gastroenterol, Nishinomiya, Hyogo 6638501, Japan

[8] Osaka Med Coll, Dept Internal Med 2, Takatsuki, Osaka 569, Japan

[9] Nagoya Univ, Grad Sch Med, Dept Gastroenterol, Nagoya, Aichi 4648601, Japan

[10] Sapporo Kosei Gen Hosp, Div Gastroenterol, Sapporo, Hokkaido, Japan

来源：

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | 2014年 / 29卷 / 01期

关键词：

capsule endoscopy; Crohn's disease; diagnosis; retention; INFLAMMATORY-BOWEL-DISEASE; METAANALYSIS; DIAGNOSIS; MANAGEMENT; YIELD; ENTEROCLYSIS; INVOLVEMENT; ENTEROSCOPY; MODALITIES; CONSENSUS;

D O I：

10.1111/jgh.12411

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Background and AimUntil the approval of patency capsule, capsule endoscopy (CE) has not been routinely applied for the diagnosis of Crohn's disease (CD) in Japan. We aimed to survey current situation of CE use for patients with CD in Japan. MethodsThe nationwide survey of 40 Japanese institutions identified 94 patients with established CD (eCD) and 80 patients with suspected CD (sCD), who were examined by CE. Types and positive rates of mucosal injury under CE and capsule retention rate were investigated. In sCD, final diagnosis after CE was also analyzed. ResultsPatients with eCD comprised 82 patients of ileitis or ileocolitis type, while 12 patients had CD of colitis type. CE identified mucosal injuries in 83 of 94 patients. Eight of 12 patients with eCD of colitis type had ileal lesions under CE, thereby being reclassified as ileocolitis type. In patients with sCD, CE detected mucosal injuries in 58 patients. Linear ulceration and cobblestone appearance were depicted in 22 and 3 patients, respectively, thereby resulting in established diagnosis of CD in 23 patients. Mucosal lesion was not found in 22 patients with sCD, who were diagnosed as not having CD. Capsule retention rate was not statistically different between patients with eCD and those with sCD (7.4% vs 6.3%, P=1.0). ConclusionsCE is useful for the evaluation of small bowel mucosal injuries in Japanese patients with sCD and eCD. Possible intestinal stricture needs to be carefully evaluated before CE even in patients with sCD.

引用

页码：96 / 101

页数：6

共 29 条

[1]

Gastroenterology 2 - Inflammatory bowel disease: clinical aspects and established and evolving therapies [J].