Assessing the effect of natural selection in malaria parasites

被引：101

作者：

Escalante, AA

Cornejo, OE

Rojas, A

Udhayakumar, V

Lal, AA

机构：

[1] Inst Venezolano Invest Cient, Caracas 1020A, Venezuela

[2] Ctr Dis Control & Prevent, Div Parasit Dis, Natl Ctr Infect Dis, Publ Hlth Serv,US Dept Hlth & Human Serv, Atlanta, GA 30341 USA

来源：

TRENDS IN PARASITOLOGY | 2004年 / 20卷 / 08期

关键词：

D O I：

10.1016/j.pt.2004.06.002

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

There are few concepts that have been used across disciplines; one of them is natural selection. The impact that this process has on parasite genetic diversity is reviewed here by discussing examples on drug resistance and vaccine antigens. Emphasis is made on how mechanisms need to be addressed rather than associations, and how such investigations were out of reach of biomedical researchers only a decade ago.

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收藏

页码：388 / 395

页数：8

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