Bacterial resistance to aminoglycoside antibiotics

被引:306
作者
Davies, J
Wright, GD
机构
[1] UNIV BRITISH COLUMBIA,DEPT IMMUNOL & MICROBIOL,VANCOUVER,BC V6T 1Z3,CANADA
[2] MCMASTER UNIV,DEPT BIOCHEM,HAMILTON,ON L8N 3Z5,CANADA
关键词
D O I
10.1016/S0966-842X(97)01033-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The aminoglycoside antibiotics are broad-spectrum antibacterial compounds that are used extensively for the treatment of many bacterial infections. In view of the current concerns over the global rise in antibiotic-resistant microorganisms, there has been renewed interest in the mechanisms of resistance to the aminoglycosides, including the superfamily of aminoglycoside-modifying enzymes.
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页码:234 / 240
页数:7
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