Recombinant interleukin-1 promotes leishmaniasis in susceptible mice

被引：4

作者：

Ajdary, S

Hosseini, MH

Alimohammadian, MH

机构：

[1] Immunology Department, Pasteur Institute of Iran, Tehran, Pasteur Ave.

来源：

MICROBIOLOGY AND IMMUNOLOGY | 1997年 / 41卷 / 03期

关键词：

BALB/c; leishmaniasis; IL-1;

D O I：

10.1111/j.1348-0421.1997.tb01202.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Interleukin-1 exacerbates leishmanial lesions in Leishmania major-infected BALB/c mice. Indomethacin can modulate the effect of IL-1, so at least part of the IL-1 effect on disease progression is due to the induction of prostaglandin synthesis.

引用

页码：281 / 283

页数：3

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