Clinical Application of Adipose Stem Cells in Plastic Surgery

被引:29
作者
Kim, Yong-Jin [1 ]
Jeong, Jae-Ho [2 ]
机构
[1] Yeungnam Univ, Coll Med, Dept Pathol, Taegu, South Korea
[2] Oblige Plast Surg Clin, Taegu 700411, South Korea
关键词
Adult Stem Cells; Adipose Stem Cells; Mesenchymal Stem Cells; Stromal Cells; Wound Healing; Regeneration; Adipose Tissue; Ischemia; Tissue Engineering; Cell Therapy; ASSISTED LIPOTRANSFER; SUPPORTIVE USE; EFFICACY; TISSUE; RECONSTRUCTION; COMPLICATIONS; AUGMENTATION; DELAY; FLAPS; AGE;
D O I
10.3346/jkms.2014.29.4.462
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Adipose stem cells (ASCs) are a type of adult stem cells that share common characteristics with typical mesenchymal stem cells. In the last decade, ASCs have been shown to be a useful cell resource for tissue regeneration. The major role of regenerative medicine in this century is based on cell therapy in which ASCs hold a key position. Active research on this new type of adult stem cell has been ongoing and these cells now have several clinical applications, including fat grafting, overcoming wound healing difficulties, recovery from local tissue ischemia, and scar remodeling. The application of cultured cells will increase the efficiency of cell therapy. However, the use of cultured stem cells is strictly controlled by government regulation to ensure patient safety. Government regulation is a factor that can limit more versatile clinical application of ASCs. In this review, current clinical applications of ASCs in plastic surgery are introduced. Future stem cell applications in clinical field including culturing and banking of ASCs are also discussed in this review.
引用
收藏
页码:462 / 467
页数:6
相关论文
共 44 条
[1]
Adipose Stromal Vascular Fraction Isolation: A Head-to-Head Comparison of Four Commercial Cell Separation Systems [J].
Aronowitz, Joel A. ;
Ellenhorn, Joshua D. I. .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2013, 132 (06) :932E-939E
[2]
The Efficacy of the Surgical Delay Procedure in Pedicle TRAM Breast Reconstruction [J].
Atisha, Dunya ;
Alderman, Amy K. ;
Janiga, Tim ;
Singal, Bonita ;
Wilkins, Edwin G. .
ANNALS OF PLASTIC SURGERY, 2009, 63 (04) :383-388
[3]
Baynosa RC, 2012, UNDERSEA HYPERBAR M, V39, P857
[4]
Cell-Assisted Lipotransfer for the Treatment of Parry-Romberg Syndrome [J].
Castro-Govea, Yanko ;
De La Garza-Pineda, Oscar ;
Lara-Arias, Jorge ;
Chacon-Martinez, Hernan ;
Mecott-Rivera, Gabriel ;
Salazar-Lozano, Abel ;
Valdes-Flores, Everardo .
ARCHIVES OF PLASTIC SURGERY-APS, 2012, 39 (06) :659-662
[5]
Autologous Platelet-Rich Plasma Mixed with Purified Fat Graft in Aesthetic Plastic Surgery [J].
Cervelli, Valerio ;
Palla, Ludovico ;
Pascali, Michele ;
De Angelis, Barbara ;
Curcio, Beniamino C. ;
Gentile, Pietro .
AESTHETIC PLASTIC SURGERY, 2009, 33 (05) :716-721
[6]
The Efficacy and Safety of Platelet-Rich Plasma and Adipose-Derived Stem Cells: An Update [J].
Choi, Jaehoon ;
Minn, Kyung Won ;
Chang, Hak .
ARCHIVES OF PLASTIC SURGERY-APS, 2012, 39 (06) :585-592
[7]
Mesenchymal stem cells in tissue repair [J].
DiMarino, Amy M. ;
Caplan, Arnold I. ;
Bonfield, Tracey L. .
FRONTIERS IN IMMUNOLOGY, 2013, 4
[8]
Long-term Complications from Breast Augmentation by Injected Polyacrylamide Hydrogel [J].
Do, Eon Rok ;
Shim, Jeong Su .
ARCHIVES OF PLASTIC SURGERY-APS, 2012, 39 (03) :267-269
[9]
The Fate of Adipocytes after Nonvascularized Fat Grafting: Evidence of Early Death and Replacement of Adipocytes [J].
Eto, Hitomi ;
Kato, Harunosuke ;
Suga, Hirotaka ;
Aoi, Noriyuki ;
Doi, Kentaro ;
Kuno, Shinichiro ;
Yoshimura, Kotaro .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2012, 129 (05) :1081-1092
[10]
The Effect of Age on the Efficacy of Human Mesenchymal Stem Cell Transplantation after a Myocardial Infarction [J].
Fan, Ming ;
Chen, Wei ;
Liu, Wei ;
Du, Guo-Qing ;
Jiang, Shu-Lin ;
Tian, Wei-Chen ;
Sun, Lu ;
Li, Ren-Ke ;
Tian, Hai .
REJUVENATION RESEARCH, 2010, 13 (04) :429-438