High-resolution imaging reveals highly selective nonface clusters in the fusiform face area

被引:149
作者
Grill-Spector, Kalanit [1 ]
Sayres, Rory
Ress, David
机构
[1] Stanford Univ, Dept Psychol, Stanford, CA 94305 USA
[2] Stanford Univ, Neurosci Program, Stanford, CA 94305 USA
[3] Brown Univ, Dept Neurosci, Providence, RI 02912 USA
关键词
D O I
10.1038/nn1745
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
A region in ventral human cortex (fusiform face area, FFA) thought to be important for face perception responds strongly to faces and less strongly to nonface objects. This pattern of response may reflect a uniform face-selective neural population or activity averaged across populations with heterogeneous selectivity. Using high-resolution functional magnetic resonance imaging (MRI), we found that the FFA has a reliable heterogeneous structure: localized subregions within the FFA highly selective to faces are spatially interdigitated with localized subregions highly selective to different object categories. We found a preponderance of face-selective responses in the FFA, but no difference in selectivity to faces compared to nonfaces. Thus, standard fMRI of the FFA reflects averaging of heterogeneous highly selective neural populations of differing sizes, rather than higher selectivity to faces. These results suggest that visual processing in this region is not exclusive to faces. Overall, our approach provides a framework for understanding the fine-scale structure of neural representations in the human brain.
引用
收藏
页码:1177 / 1185
页数:9
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