Hepatotoxicity, leucopenia and neutropenia associated with olanzapine therapy

被引：12

作者：

Tchernichovsky, E

Sirota, P

机构：

[1] Abarbanel Mental Hlth Ctr, IL-59100 Bat Yam, Israel

[2] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel

来源：

INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE | 2004年 / 8卷 / 03期

关键词：

olanzapine; drug-induced hepatitis; neutropenia; leucopenia;

D O I：

10.1080/13651500410005577

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Hepatotoxicity, leukopenia and neutropenia are rarely associated with atypical antipsychotic drug therapy. The authors describe a case of a schizophrenic patient, who was treated twice with olanzapine, and who developed an increase of hepatic enzymes, jaundice, reduced WBC, neutropenia, and a high temperature. The patient was diagnosed as suffering from hepatocellular hepatitis, neutropenia and leucopenia. Neuroleptic treatment was discontinued immediately and the patient exhibited consequential clinical improvement. A review of the literature is included.

引用

收藏

页码：173 / 177

页数：5

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