The synthesis of 3-phosphonocyclobutyl amino acid analogues of glutamic acid via diethyl 3-oxycyclobutylphosphonate, a versatile synthetic intermediate

被引：15

作者：

Hanrahan, JR

Taylor, PC

Errington, W

机构：

[1] Department of Chemistry, University of Warwick, Coventry

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1997年 / 04期

关键词：

D O I：

10.1039/a604898f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A range of novel 3-phosphonocyclobutyl amino acids have been prepared via the versatile synthetic intermediate, diethyl 3-oxocyclobutylphosphonate, which is prepared in three steps from diethyl methylphosphonate. Elaboration of the 3-oxo functionality readily facilitates the synthesis of the 3-phosphonocyclobutyl amino acids.

引用

页码：493 / 502

页数：10

共 26 条

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