CO2 sensing in fungi and beyond

被引:118
作者
Bahn, Yong-Sun [1 ]
Muhlschlegel, Fritz A.
机构
[1] Soongsil Univ, Dept Bioinformat & Life Sci, Seoul 156743, South Korea
[2] Univ Kent, Dept Biosci, Canterbury CT2 7NJ, Kent, England
基金
英国惠康基金;
关键词
D O I
10.1016/j.mib.2006.09.003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Carbon dioxide is not only an important gaseous molecule for maintenance of the biosphere homeostasis, but is also a crucial signalling cue in living cells. Fungal pathogens, including Candida albicans and Cryptococcus neoformans, must adapt to dramatic changes in CO2 levels during colonization and subsequent infection of their human host. Recent reports provide insight into how pathogenic fungi sense environmental CO2 and the role of carbonic anhydrase and fungal adenylyl cyclase in CO2 sensing.
引用
收藏
页码:572 / 578
页数:7
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