Determination of paracetamol:: Historical evolution

被引：233

作者：

Bosch, M. Espinosa ^{[1
]}

Sanchez, A. J. Ruiz ^{[1
]}

Rojas, F. Sanchez ^{[1
]}

Ojeda, C. Bosch ^{[1
]}

机构：

[1] Univ Malaga, Fac Sci, Dept Analyt Chem, E-29071 Malaga, Spain

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2006年 / 42卷 / 03期

关键词：

paracetamol; review; pharmaceutical formulations; biological fluids;

D O I：

10.1016/j.jpba.2006.04.007

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Paracetamol is a common analgesic and antipyretic drug that is used for the relief of fever, headaches and other minor aches and pains. Their determination in pharmaceuticals is of paramount importance, since an overdose of paracetamol can cause fulminating hepatic necrosis and other toxic effects. Many analytical methodologies have been proposed for the determination of paracetamol. The aim of the present study is to evaluate the utility of different techniques for quantification of paracetamol content in pharmaceutical formulations and biological samples. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：291 / 321

页数：31

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