Stereochemistry of the methyl->methylene elimination in the enzyme-catalysed cyclization of geranyl diphosphate to (4S)-limonene

被引：9

作者：

Coates, RM

Elmore, CS

Croteau, RB

Williams, DC

Morimoto, H

Williams, PG

机构：

[1] WASHINGTON STATE UNIV,INST BIOL CHEM,PULLMAN,WA 99164

[2] EO LAWRENCE BERKELEY NATL LAB,NATL TRITIUM LABELLING FACIL,BERKELEY,CA 94720

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 21期

关键词：

D O I：

10.1039/a704370h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The cyclization of (R)-[9-H-2(1),H-3(1)]geranyl diphosphate catalysed by a recombinant form of(4S)-limonene synthase from spearmint leaf (Mentha spicata)is terminated predominantly by re-facial, anti proton elimination at the cis methyl group, producing (4S, 8E)-[8-H-2(1),H-3(1)] limonene.

引用

页码：2079 / 2080

页数：2

共 20 条

[1]

ALONSO WR, 1992, J BIOL CHEM, V267, P7582

[2] PREPARATION AND USE OF LIET3BT AND LIALT4 AT MAXIMUM SPECIFIC ACTIVITY [J].