A novel binaphthylamine auxiliary for asymmetric imidate Claisen rearrangement

被引：19

作者：

Hungerhoff, B ^{[1
]}

Metz, P ^{[1
]}

机构：

[1] Tech Univ Dresden, Inst Organ Chem, D-01062 Dresden, Germany

来源：

TETRAHEDRON | 1999年 / 55卷 / 52期

关键词：

metallation; rearrangements; imidic acids and derivatives; enantiocontrol;

D O I：

10.1016/S0040-4020(99)00978-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enantiomerically pure methyl substituted binaphthylamine 7 has been prepared via a regioselective directed ortho-metallation of the methoxy substituted binaphthyl carboxylic acid 5 as the key step and used as an auxiliary for asymmetric imidate Claisen rearrangement. Excellent auxiliary induction as well as simple (anti/syn) diastereoselection was achieved. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：14941 / 14946

页数：6

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