Rapid screening of cervical smears as a method of internal quality control - For how long should we rescreen?

被引:36
作者
Farrell, DJ [1 ]
Bilkhu, S [1 ]
Gibson, LM [1 ]
Cummings, L [1 ]
Wadehra, V [1 ]
机构
[1] NEWCASTLE GEN HOSP,DEPT CLIN CYTOL,NEWCASTLE TYNE NE4 6BE,TYNE & WEAR,ENGLAND
关键词
mass rescreening; cervical smears; quality control;
D O I
10.1159/000332451
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
OBJECTIVE: To compare the effectiveness of vapid screening of cervical smears as a method of internal quality control with 10% random rescreening. STUDY DESIGN: From June 5 to July 14, 1995 (6 weeks), all consecutive cervical smears received in the department (n = 8,800) were entered into the study and were prescreezed for a duration of 30 seconds (n = 2,938), 1 minute (n = 2,925) or 2 minutes (n = 2,937) over a period of 2 weeks each. RESULTS: Rapid screening of all negative and unsatisfactory smears detected more cytologic abnormalities than would be expected with 10% random rescreening. Thirty-second rapid screening of all negative and unsatisfactory smears was more efficient in detecting false negatives than screening a proportion of the smears for longer periods of time. Rapid screening was also a very effective method of detecting severe cytologic abnormalities in unscreened smears, detecting over 90% of high grade lesions. CONCLUSION: Rapid rescreening of negative and unsatisfactory cervical smears is recommended as a very effective method of internal quality control. It is superior to 10% random rescreening in reducing the false negative rate. Thirty-second rapid rescreening is the most efficient period for which smears should be screened. Rapid screening of unscreened smears could be used as a means of selecting patients for prompt referral when a laboratory backlog exists.
引用
收藏
页码:251 / 260
页数:10
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