Evaluation of the Nanosphere Verigene BC-GN Assay for Direct Identification of Gram-Negative Bacilli and Antibiotic Resistance Markers from Positive Blood Cultures and Potential Impact for More-Rapid Antibiotic Interventions

被引：55

作者：

Hill, Joseph T. ^{[1
]}

Tran, Kim-Dung T. ^{[1
]}

Barton, Karen L. ^{[2
]}

Labreche, Matthew J. ^{[2
]}

Sharp, Susan E. ^{[1
]}

机构：

[1] Kaiser Permanente, Sunnyside Med Ctr, Dept Mol Microbiol, Portland, OR 97201 USA

[2] Kaiser Permanente, Sunnyside Med Ctr, Reg Antimicrobial Stewardship Program, Portland, OR USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2014年 / 52卷 / 10期

关键词：

OPTIMIZING ANTIMICROBIAL THERAPY; CLOSTRIDIUM-DIFFICILE; BACTEREMIA; DIARRHEA;

D O I：

10.1128/JCM.01537-14

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The Verigene BC-GN assay correctly identified all 51 Gram-negative bacilli (GNB) from positive blood cultures and all 14 carbapenemase enzymes tested. The assay gave organism identification (ID) results an average of 24 h faster compared to conventional identifications. Medical management could have been modified for 31.8% of patients an average 33 h sooner. In conclusion, the BC-GN assay is a very accurate, rapid assay which would allow for more-immediate medical management decisions in patients with bacteremia from GNB.

引用

页码：3805 / 3807

页数：3

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