Cross-coupling of alkyl halides with aryl Grignard reagents catalyzed by a low-valent iron complex

被引：328

作者：

Martin, R ^{[1
]}

Fürstner, A ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 30期

关键词：

alkyl halides; cross-coupling; Grignard reagents; iron;

D O I：

10.1002/anie.200460504

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A striking reversal of the usual reactivity pattern of aryl Grignard reagents is observed for reactions in the presence of catalytic amounts of the bare" ferrate complex [Li(tmeda)]2[Fe(C2H 4)4] (1). Highly reduced iron-magnesium clusters may play a decisive role in the exceptionally facile and chemoselective cross-coupling reaction with alkyl halides (see scheme)."

引用

页码：3955 / 3957

页数：3

共 68 条

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