Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery

被引:156
作者
de Ligt, RAF [1 ]
Kourounakis, AP [1 ]
Ijzerman, AP [1 ]
机构
[1] Leiden Amsterdam Ctr Drug Res, Div Med Chem, NL-2300 RA Leiden, Netherlands
关键词
GPCR; inverse agonism; neutral antagonist; negative efficacy; review; implications drug discovery;
D O I
10.1038/sj.bjp.0703311
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
[No abstract available]
引用
收藏
页码:1 / 12
页数:12
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