Highly diastereoselective epoxidation of cholest-5-ene derivatives catalyzed by polymer-supported manganese(III) porphyrins

被引：33

作者：

Du, CP ^{[1
]}

Li, ZK ^{[1
]}

Wen, XM ^{[1
]}

Wu, J ^{[1
]}

Yu, XQ ^{[1
]}

Yang, M ^{[1
]}

Xie, RG ^{[1
]}

机构：

[1] Sichuan Univ, Sichuan Key Lab Green Chem & Technol, Dept Chem, Chengdu 610064, Peoples R China

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2004年 / 216卷 / 01期

基金：

中国国家自然科学基金;

关键词：

diastereoselective epoxidation; cholest-5-ene derivatives; supported metalloporphyrins;

D O I：

10.1016/j.molcata.2003.12.039

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Manganese(III) 5,10,15-tris(tolyl)-20-(4-hydroxyphenyl) porphyrin covalently attached to Merrifield's peptide resin (MPR) was prepared. The catalysts exhibit high reactivity and beta-selectivity toward the epoxidation of cholest-5-ene derivatives with PhIO. Under mild reaction conditions, the catalyst was consecutively reused four times without detectable catalyst leaching and gave over 90% epoxide yield and over 99% beta-selectivity. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：7 / 12

页数：6

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