A new mechanism of action proposed for ramoplanin

被引:81
作者
Lo, MC
Men, H
Branstrom, A
Helm, J
Yao, N
Goldman, R
Walker, S [1 ]
机构
[1] Princeton Univ, Dept Chem, Princeton, NJ 08544 USA
[2] Princeton Univ, Princeton Mat Inst, Princeton, NJ 08544 USA
[3] Incara Pharmaceut, Dept Biol, Cranbury, NJ 08512 USA
关键词
D O I
10.1021/ja000182x
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:3540 / 3541
页数:2
相关论文
共 22 条
[1]   Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic [J].
Breukink, E ;
Wiedemann, I ;
van Kraaij, C ;
Kuipers, OP ;
Sahl, HG ;
de Kruijff, B .
SCIENCE, 1999, 286 (5448) :2361-2364
[2]   Role of lipid-bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics [J].
Brötz, H ;
Josten, M ;
Wiedemann, I ;
Schneider, U ;
Götz, F ;
Bierbaum, G ;
Sahl, HG .
MOLECULAR MICROBIOLOGY, 1998, 30 (02) :317-327
[3]   The lantibiotic mersacidin inhibits peptidoglycan biosynthesis at the level of transglycosylation [J].
Brotz, H ;
Bierbaum, G ;
Reynolds, PE ;
Sahl, HG .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 246 (01) :193-199
[4]   The lantibiotic mersacidin inhibits peptidoglycan synthesis by targeting lipid II [J].
Brötz, H ;
Bierbaum, G ;
Leopold, K ;
Reynolds, PE ;
Sahl, HG .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (01) :154-160
[5]  
Cann J R, 1978, Methods Enzymol, V48, P299
[6]   Vancomycin derivatives that inhibit peptidoglycan biosynthesis without binding D-Ala-D-Ala [J].
Ge, M ;
Chen, Z ;
Onishi, HR ;
Kohler, J ;
Silver, LL ;
Kerns, R ;
Fukuzawa, S ;
Thompson, C ;
Kahne, D .
SCIENCE, 1999, 284 (5413) :507-511
[7]   SELF-ASSEMBLING ORGANIC NANOTUBES BASED ON A CYCLIC PEPTIDE ARCHITECTURE [J].
GHADIRI, MR ;
GRANJA, JR ;
MILLIGAN, RA ;
MCREE, DE ;
KHAZANOVICH, N .
NATURE, 1993, 366 (6453) :324-327
[8]   Chlorobiphenyl-desleucyl-vancomycin inhibits the transglycosylation process required for peptidoglycan synthesis in bacteria in the absence of dipeptide binding [J].
Goldman, RC ;
Baizman, ER ;
Longley, CB ;
Branstrom, AA .
FEMS MICROBIOLOGY LETTERS, 2000, 183 (02) :209-214
[9]   The kinetic characterization of Escherichia coli MurG using synthetic substrate analogues [J].
Ha, S ;
Chang, E ;
Lo, MC ;
Men, H ;
Park, P ;
Ge, M ;
Walker, S .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (37) :8415-8426
[10]   Self-assembling peptide nanotubes [J].
Hartgerink, JD ;
Granja, JR ;
Milligan, RA ;
Ghadiri, MR .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (01) :43-50