Genetics of spondyloarthritis

被引：23

作者：

Breban, Maxime ^{[1
]}

机构：

[1] Hop Cochin, CNRS, INSERM, U567,CNRS,Inst Cochin,UMR8104,IFR116, F-75014 Paris, France

来源：

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY | 2006年 / 20卷 / 03期

关键词：

genetic; spondyloarthritis; ankylosing spondylitis; family study; psoriatic arthritis;

D O I：

10.1016/j.berh.2006.03.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This chapter reviews evidence from family and twin studies supporting the strong genetic predisposition of the spondyloarthriticles (SpA), which is only partially attributable to the major histocompatibility locus. The current concept of SpA heterogeneity has been challenged by family studies which showed that all articular and extra-articular manifestations were linked together, and most likely to the same genetic factors.

引用

页码：593 / 599

页数：7

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