First Detection of Co-circulation of West Nile and Usutu Viruses in Equids in the South-west of Tunisia

被引：52

作者：

Ben Hassine, T. ^{[1
]}

De Massis, F. ^{[2
]}

Calistri, P. ^{[2
]}

Savini, G. ^{[2
]}

Mohamed, B. BelHaj ^{[1
]}

Ranen, A. ^{[3
]}

Di Gennaro, A. ^{[2
]}

Sghaier, S. ^{[4
]}

Hammami, S. ^{[1
]}

机构：

[1] Ctr Natl Veille Zoosanit, Tunis 1082, Tunisia

[2] Ist Zooprofilatt Sperimentale Abruzzo & Molise G, Teramo, Italy

[3] Commissariat Reg Dev Agr Kebili, Kebili, Tunisia

[4] Inst Rech & Vet Tunisie, Tunis, Tunisia

来源：

TRANSBOUNDARY AND EMERGING DISEASES | 2014年 / 61卷 / 05期

关键词：

West Nile Virus; Usutu Virus; co-circulation; equids; southern west; Tunisia; SEROLOGICAL EVIDENCE; EMERGENCE; HORSES; ELISA;

D O I：

10.1111/tbed.12259

中图分类号：

R51 [传染病];

学科分类号：

100201 [内科学];

摘要：

In the last fifteen years, West Nile Virus (WNV) has dramatically expanded its geographic range and is now considered the most widespread arbovirus in the world. In Tunisia, West Nile Fever (WNF) outbreaks were reported in humans in 1997, 2003 and 2012. Usutu Virus (USUV), which is a 'new' emerging Flavivirus antigenically close to WNV, has never been reported in Tunisia. A serological investigation in 284 equids was conducted in 2012 in the southern west region of the country to assess the presence and prevalence of the WNV and USUV infection. Of the 284 samples tested by competitive enzyme-linked immunoassay, 129 were positive. Of these, 120 (42.3%) had WNV-specific neutralizing antibodies. The prevalence was significantly higher in areas closer to the oasis compared with that of the surrounding arid areas. Antibody titres against USUV were also reported in 10 equids. This was the first evidence of USUV circulation in Tunisia. Data recorded by this study indicate that WNV and USUV have circulated/are circulating in the region and that there is an urgent need to adapt the current surveillance programmes to this new scenario.

引用

页码：385 / 389

页数：5

共 37 条

[1]

Evaluation of an enzyme-linked immunosorbent assay for detection of West Nile virus infection based on a recombinant envelope protein produced in Trichoplusia ni larvae [J].