Palladium-catalyzed arylation of α-methylene-γ-butyrolactone:: 3-benzylfuran-2(5H)-ones vs (Z)-benzylidene-γ-butyrolactones and their reduction to 3-benzyl-γ butyrolactones

被引：30

作者：

Arcadi, A

Chiarini, M

Marinelli, F

Berente, Z

Kollàr, L

机构：

[1] Dipartimento Chim Ingn Chim & Mat, I-67010 Coppito, AQ, Italy

[2] Univ Pecs, Sch Med, Dept Biochem, H-7643 Pecs, Hungary

[3] Janus Pannonius Univ, Dept Inorgan Chem, H-7624 Pecs, Hungary

[4] Hungarian Acad Sci, Res Grp Chem Sensors, H-7624 Pecs, Hungary

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 01期

关键词：

D O I：

10.1021/ol9912130

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The palladium-catalyzed arylation of the alpha-methylene-gamma-butyrolactone proceeds in good yields and may be directed toward the synthesis of 3-benzylfuran-2(5H)-ones when the starting aryl iodides contain strongly electron withdrawing groups. The combined palladium-catalyzed arylation/hydrogenation of the alpha-methylene-gamma-butyrolactone represents a new simple entry into functionalized alpha-benzyl-gamma-butyrolactones.

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页码：69 / 72

页数：4

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